Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP15229 | Target Name | SLF2 |
|---|---|---|---|
| Target Synonyms | SLF2; C10orf6; FAM178A; SMC5-SMC6 complex localization factor protein 2; Smc5/6 localization factor 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IX21 |
|---|
Uniprot Id
Q8IX21
Target Species
Human
Target Name
SLF2
Target Full Name
SMC5-SMC6 complex localization factor protein 2
Target Function
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions.
Target Subcellular Location
Nucleus.
Target Protein Families
FAM178 family
Target Tissue Specificity
Widely expressed. Expressed at higher level in skeletal muscle and at slightly lower level in brain, liver and heart, than in lung, kidney, spleen and thymus.
Target Synonyms
SLF2; C10orf6; FAM178A; SMC5-SMC6 complex localization factor protein 2; Smc5/6 localization factor 1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
