Recombinant Human Protein lin-7 homolog C (LIN7C)

Cat.No	ACP11442	Target Name	LIN7C
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-197	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP11442

Target Name

LIN7C

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

2-197

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9NUP9

Background Information

Uniprot Id

Q9NUP9
Target Species

Human
Target Name

LIN7C
Target Full Name

Protein lin-7 homolog C
Target Function

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Target Subcellular Location

Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Cell junction, synapse, postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction.
Target Protein Families

Lin-7 family
Target Synonyms

hLin 7; hLin7; LIN 7; Lin 7 homolog A; LIN 7A; LIN 7B; LIN 7C; Lin-7C; Lin7 homolog A; LIN7A; LIN7C; LIN7C_HUMAN; MALS 1; MALS; MALS-3; MALS1; Mammalian LIN 7 1; Mammalian lin seven protein 1; Mammalian lin-seven protein 3; Mammalian LIN7 1; MGC148143; Protein lin 7 homolog B; Protein lin 7 homolog C; Protein lin-7 homolog C; protein lin7 homolog A ; Tax interaction protein 33; TIP 33; TIP33; VELI 1; Veli 1 protein; Veli-3; VELI1; Velis; Vertebrate LIN 7 homolog 1; Vertebrate lin-7 homolog 3; Vertebrate LIN7 homolog 1
Target Background

Enables L27 domain binding activity and cytoskeletal protein binding activity. Involved in morphogenesis of an epithelial sheet. Located in cell-cell junction; cytoplasm; and plasma membrane. Part of MPP7-DLG1-LIN7 complex.

Recombinant Human Protein lin-7 homolog C (LIN7C)

Specifications

Immunogen Information

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