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Recombinant Human Protein LMBR1L (LMBR1L), Truncated

ACP06059

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06059 Target NameLMBR1L
Target SynonymsLMBR1L; KIAA1174; LIMR; UNQ458/PRO783Protein LMBR1L; Limb region 1 protein homolog-like; Lipocalin-1-interacting membrane receptor; LIMRFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6UX01
Background Information
  • Uniprot Id

    Q6UX01

  • Target Species

    Human

  • Target Name

    LMBR1L

  • Target Full Name

    Protein LMBR1L

  • Target Function

    Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels. Acts as a LCN1 receptor and can mediate its endocytosis.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    LIMR family

  • Target Tissue Specificity

    Expressed in testis, pituitary gland, adrenal gland, trachea, placenta, thymus, cerebellum, stomach, mammary gland, spinal cord. A weaker expression is detected in colon, pancreas, and prostate.

  • Target Synonyms

    LMBR1L; KIAA1174; LIMR; UNQ458/PRO783Protein LMBR1L; Limb region 1 protein homolog-like; Lipocalin-1-interacting membrane receptor; LIMR

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