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| Cat.No | ACP15316 | Target Name | TIPARP |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-657 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z3E1 |
|---|
Uniprot Id
Q7Z3E1
Target Species
Human
Target Name
TIPARP
Target Full Name
Protein mono-ADP-ribosyltransferase TIPARP
Target Function
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.
Target Subcellular Location
Nucleus.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; AW558171; DDF1; DKFZp434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP 1; PARP 7; PARP-7; PARPT_HUMAN; pART14; Poly [ADP ribose] polymerase 7; Poly [ADP-ribose] polymerase 7; TCDD inducible poly(ADP ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; TIPARP
Target Background
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.
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