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Recombinant Human Protein PAXX (C9orf142)

ACP12348

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12348 Target NamePAXX
Target SynonymsC9orf142; Chromosome 9 open reading frame 142 ; CI142_HUMAN; PAXX; Uncharacterized protein C9orf142; XLSFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-204
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BUH6
Background Information
  • Uniprot Id

    Q9BUH6

  • Target Species

    Human

  • Target Name

    PAXX

  • Target Full Name

    Protein PAXX

  • Target Function

    Non-essential DNA repair protein involved in DNA non-homologous end joining (NHEJ); participates in double-strand break (DSB) repair and V(D)J recombination. May act as a scaffold required for accumulation of the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at double-strand break sites and promote the assembly and/or stability of the NHEJ machinery. Involved in NHEJ by promoting the ligation of blunt-ended DNA ends. Together with NHEJ1/XLF, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends. Constitutes a non-essential component of classical NHEJ: has a complementary but distinct function with NHEJ1/XLF in DNA repair. Able to restrict infection by herpesvirus 1 (HSV-1) via an unknown mechanism

  • Target Subcellular Location

    Nucleus. Chromosome.; Cytoplasm.

  • Target Synonyms

    C9orf142; Chromosome 9 open reading frame 142 ; CI142_HUMAN; PAXX; Uncharacterized protein C9orf142; XLS

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