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Recombinant Human Protein phosphatase 1B (PPM1B)

ACP03095

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Specifications

Cat.No	ACP03095	Target Name	PPM1B
Target Synonyms	1B, Mg2+/Mn2+ dependent	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-192aa
Mol Weight	36.6kDa	Protein Length	Full Length of Isoform Beta-X
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75688

Background Information

Uniprot Id

O75688
Target Species

Human
Target Name

PPM1B
Target Full Name

Protein phosphatase 1B
Target Function

Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Target Subcellular Location

Cytoplasm, cytosol. Membrane; Lipid-anchor.
Target Protein Families

PP2C family
Target Tissue Specificity

Highly expressed in heart and skeletal muscle.
Target Research Area

Signal Transduction
Target Synonyms

MGC21657; OTTHUMP00000158953; OTTHUMP00000158954; OTTHUMP00000158955; OTTHUMP00000202394; OTTHUMP00000202395; OTTHUMP00000202399; PP2C beta; PP2C beta X; PP2C-beta; PP2CB; PP2Cbeta; PPC2BETAX; PPM 1B; Ppm1b; PPM1B_HUMAN; Protein phosphatase 1B (formerly 2C) magnesium dependent beta isoform; Protein phosphatase 1B; Protein phosphatase 1B magnesium dependent beta isoform; Protein phosphatase 2C beta isoform; Protein phosphatase 2C isoform beta; Protein phosphatase 2C like protein; Protein phosphatase, Mg2+/Mn2+ dependent, 1B

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Recombinant Human Protein phosphatase 1B (PPM1B)

Specifications

Immunogen Information

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