Recombinant Human Protein Red (IK)

Cat.No	ACP18518	Target Name	IK
Target Synonyms	chondrosarcoma associated protein 2 ; CSA2 ; Cytokine IK; IK; IK cytokine down regulator of HLA II ; IK factor; IK Gene; prer protein; Protein Red; Protein RER; RD element; RED protein; RED_HUMAN; RER	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-557
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP18518

Target Name

Target Synonyms

chondrosarcoma associated protein 2 ; CSA2 ; Cytokine IK; IK; IK cytokine down regulator of HLA II ; IK factor; IK Gene; prer protein; Protein Red; Protein RER; RD element; RED protein; RED_HUMAN; RER

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-557

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q13123

Background Information

Uniprot Id

Q13123
Target Species

Human
Target Name

IK
Target Full Name

Protein Red
Target Function

Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1.; (Microbial infection) Required, together with SMU1, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Target Subcellular Location

Nucleus. Nucleus, nucleoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families

RED family
Target Tissue Specificity

Ubiquitous.
Target Synonyms

chondrosarcoma associated protein 2 ; CSA2 ; Cytokine IK; IK; IK cytokine down regulator of HLA II ; IK factor; IK Gene; prer protein; Protein Red; Protein RER; RD element; RED protein; RED_HUMAN; RER
Target Background

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.

Recombinant Human Protein Red (IK)

Specifications

Immunogen Information

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