Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP21122 | Target Name | SPRY3 |
|---|---|---|---|
| Target Synonyms | SPRY3; Protein sprouty homolog 3; Spry-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-288 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43610 |
|---|
Uniprot Id
O43610
Target Species
Human
Target Name
SPRY3
Target Full Name
Protein sprouty homolog 3
Target Function
Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Sprouty family
Target Tissue Specificity
Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level). Expressed in the myocardium of the heart.
Target Synonyms
SPRY3; Protein sprouty homolog 3; Spry-3
Target Background
Involved in negative regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be active in cytosol.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
