Recombinant Human Protein transport protein Sec16B (SEC16B), Truncated

Uniprot Id

Q96JE7

Target Species

Human

Target Name

SEC16B

Target Full Name

Protein transport protein Sec16B

Target Function

Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.

Target Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.

Target Protein Families

SEC16 family

Target Tissue Specificity

Ubiquitous.

Target Synonyms

DKFZp686C2486; FLJ23871; FLJ25761; FLJ33652; FLJ36620; KIAA1928; Leucine zipper transcription regulator 2; LZTR 2; PGPR p117; Protein SEC16 homolog B; Protein transport protein Sec16B; Regucalcin gene promoter region related protein; Regucalcin gene promoter region related protein p117; Regucalcin gene promoter region-related protein p117; RGPR; RGPR p117; RGPR-p117; SC16B_HUMAN; SEC16 homolog B (S. cerevisiae); SEC16 homolog B; SEC16B; SEC16S

Target Background

SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).