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| Cat.No | ACP13231 | Target Name | NSUN4 |
|---|---|---|---|
| Target Synonyms | 5 methylcytosine rRNA methyltransferase NSUN4; EC=2.1.1.-; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; Nsun4; NSUN4_HUMAN; Putative methyltransferase NSUN4; RP4-603I14.2; Shtap; Sperm head and tail associated protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 26-384 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96CB9 |
|---|
Uniprot Id
Q96CB9
Target Species
Human
Target Name
NSUN4
Target Full Name
5-cytosine rRNA methyltransferase NSUN4
Target Function
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
Target Synonyms
5 methylcytosine rRNA methyltransferase NSUN4; EC=2.1.1.-; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; Nsun4; NSUN4_HUMAN; Putative methyltransferase NSUN4; RP4-603I14.2; Shtap; Sperm head and tail associated protein
Target Background
Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in rRNA methylation. Part of mitochondrial large ribosomal subunit.
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