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| Cat.No | ACP14976 | Target Name | RPAP2 |
|---|---|---|---|
| Target Synonyms | RPAP2; C1orf82; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; EC 3.1.3.16; RNA polymerase II-associated protein 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-612 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IXW5 |
|---|
Uniprot Id
Q8IXW5
Target Species
Human
Target Name
RPAP2
Target Full Name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Target Function
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.
Target Protein Families
RPAP2 family
Target Synonyms
RPAP2; C1orf82; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; EC 3.1.3.16; RNA polymerase II-associated protein 2
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