Recombinant Human Rab11 family-interacting protein 1 (RAB11FIP1), Truncated

Uniprot Id

Q6WKZ4

Target Species

Human

Target Name

RAB11FIP1

Target Full Name

Rab11 family-interacting protein 1

Target Function

A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.

Target Subcellular Location

Recycling endosome. Note=Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).; [Isoform 2]: Cytoplasmic vesicle, phagosome membrane. Note=Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).

Target Tissue Specificity

Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine.

Target Synonyms

FLJ22524; FLJ22622; HGNC:30265; MGC78448; No Rab11 binding protein 1A; NOEL1A; Rab coupling protein; Rab effector protein; Rab interacting recycling protein; Rab-coupling protein; RAB11 family interacting protein 1 (class I); Rab11 family interacting protein 1D; Rab11 family-interacting protein 1; Rab11 FIP1; Rab11-FIP1; RAB11FIP1; RCP; RFIP1_HUMAN

Target Background

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome.