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| Cat.No | ACP11842 | Target Name | RSPH9 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-276 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H1X1 |
|---|
Uniprot Id
Q9H1X1
Target Species
Human
Target Name
RSPH9
Target Full Name
Radial spoke head protein 9 homolog
Target Function
Component of the axonemal radial spoke head which plays an important role in ciliary motility. Essential for both the radial spoke head assembly and the central pair microtubule stability in ependymal motile cilia. Required for motility of olfactory and neural cilia and for the structural integrity of ciliary axonemes in both 9+0 and 9+2 motile cilia.
Target Involvement
Ciliary dyskinesia, primary, 12 (CILD12)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Cell projection, kinocilium.
Target Protein Families
Flagellar radial spoke RSP9 family
Target Synonyms
C6orf206; Chromosome 6 open reading frame 206; CILD12; FLJ30845; Mitochondrial ribosomal protein S18A like 1; MRPS18AL1; Radial spoke head 9 homolog; Radial spoke head protein 9 homolog; RSPH 9; rsph9; RSPH9_HUMAN; Uncharacterized protein C6orf206
Target Background
This gene encodes a protein thought to be a component of the radial spoke head in motile cilia and flagella. Mutations in this gene are associated with primary ciliary dyskinesia 12. Alternative splicing results in multiple transcript variants.
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