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| Cat.No | ACP17315 | Target Name | RFTN2 |
|---|---|---|---|
| Target Synonyms | Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-501 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q52LD8 |
|---|
Uniprot Id
Q52LD8
Target Species
Human
Target Name
RFTN2
Target Full Name
Raftlin-2
Target Function
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
Target Subcellular Location
Cell membrane; Lipid-anchor.
Target Protein Families
Raftlin family
Target Synonyms
Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN
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