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Recombinant Human Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2), Truncated

ACP21555

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21555 Target NameRASGRF2
Target SynonymsGRF2; Ras guanine nucleotide exchange factor 2; Ras protein specific guanine nucleotide releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2; RASGRF2; RGRF2_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO14827
Background Information
  • Uniprot Id

    O14827

  • Target Species

    Human

  • Target Name

    RASGRF2

  • Target Full Name

    Ras-specific guanine nucleotide-releasing factor 2

  • Target Function

    Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Widely expressed with higher expression in brain, followed by heart, lung, pancreas and kidney. Detected in placenta. Expressed in brain and lung (at protein level).

  • Target Synonyms

    GRF2; Ras guanine nucleotide exchange factor 2; Ras protein specific guanine nucleotide releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2; RASGRF2; RGRF2_HUMAN

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