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| Cat.No | ACP21941 | Target Name | RCCD1 |
|---|---|---|---|
| Target Synonyms | MGC14386; RCC1 domain-containing protein 1; RCCD1; RCCD1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-376 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A6NED2 |
|---|
Uniprot Id
A6NED2
Target Species
Human
Target Name
RCCD1
Target Full Name
RCC1 domain-containing protein 1
Target Function
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
Target Subcellular Location
Chromosome.
Target Synonyms
MGC14386; RCC1 domain-containing protein 1; RCCD1; RCCD1_HUMAN
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