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| Cat.No | ACP16215 | Target Name | REG3G |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 27-175 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UW15 |
|---|
Uniprot Id
Q6UW15
Target Species
Human
Target Name
REG3G
Target Full Name
Regenerating islet-derived protein 3-gamma
Target Function
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
Target Subcellular Location
Secreted. Cytoplasm.
Target Tissue Specificity
Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta.
Target Research Area
Immunology
Target Synonyms
LPPM429; Pancreatitis-associated protein 1B; Pancreatitis-associated protein IB; PAP IB; PAP-1B; PAP1B; PAPIB; REG III; Reg III-gamma; REG-3-gamma; REG3G; REG3G_HUMAN; Regenerating islet derived 3 gamma; Regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein III-gamma; UNQ429
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