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| Cat.No | ACP21636 | Target Name | RGS12 |
|---|---|---|---|
| Target Synonyms | RGS12; Regulator of G-protein signaling 12; RGS12 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14924 |
|---|
Uniprot Id
O14924
Target Species
Human
Target Name
RGS12
Target Full Name
Regulator of G-protein signaling 12
Target Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.; Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
Target Subcellular Location
Nucleus. Cytoplasm. Cell projection, dendrite. Cell junction, synapse.; [Isoform 5]: Nucleus matrix.
Target Tissue Specificity
Isoform 3 is brain specific.
Target Synonyms
RGS12; Regulator of G-protein signaling 12; RGS12
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