Recombinant Human Reticulon-4 receptor-like 1 (RTN4RL1)

Cat.No	ACP15283	Target Name	RTN4RL1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	25-420	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP15283

Target Name

RTN4RL1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

25-420

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q86UN2

Background Information

Uniprot Id

Q86UN2
Target Species

Human
Target Name

RTN4RL1
Target Full Name

Reticulon-4 receptor-like 1
Target Function

Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Perikaryon. Cell projection.
Target Protein Families

Nogo receptor family
Target Tissue Specificity

Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.
Target Synonyms

DKFZp547J144; NgR 3; NgR3; NGRH 2; NGRH2; NGRL2; Nogo 66 receptor homolog 2; Nogo 66 receptor related protein 3; Nogo receptor like 2; Nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; R4RL1_HUMAN; Reticulon 4 receptor like 1; Reticulon-4 receptor-like 1; RTN4RL1
Target Background

Enables signaling receptor activity. Predicted to be involved in negative regulation of axon regeneration. Located in cell surface. Is anchored component of plasma membrane.

Recombinant Human Reticulon-4 receptor-like 1 (RTN4RL1)

Specifications

Immunogen Information

Inquire Recombinant Human Reticulon-4 receptor-like 1 (RTN4RL1) Now

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