Home Products Proteins Recombinant Proteins Recombinant Human Rho guanine nucleotide exchange factor 4 (ARHGEF4)

Recombinant Human Rho guanine nucleotide exchange factor 4 (ARHGEF4)

ACP10923

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP10923	Target Name	ARHGEF4
Target Synonyms	ARHGEF4; KIAA1112Rho guanine nucleotide exchange factor 4; APC-stimulated guanine nucleotide exchange factor 1; Asef; Asef1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-690
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NR80

Background Information

Uniprot Id

Q9NR80
Target Species

Human
Target Name

ARHGEF4
Target Full Name

Rho guanine nucleotide exchange factor 4
Target Function

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Target Subcellular Location

[Isoform 3]: Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity

Expressed at high levels in the brain, skeletal muscle and testis and at low levels in the kidney, lung, small intestine, ovary and prostate. Expression is aberrantly enhanced in most colorectal tumors.
Target Synonyms

ARHGEF4; KIAA1112Rho guanine nucleotide exchange factor 4; APC-stimulated guanine nucleotide exchange factor 1; Asef; Asef1

Inquire Recombinant Human Rho guanine nucleotide exchange factor 4 (ARHGEF4) Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Rho guanine nucleotide exchange factor 4 (ARHGEF4)

Specifications

Immunogen Information

Inquire Recombinant Human Rho guanine nucleotide exchange factor 4 (ARHGEF4) Now

Related Products