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Recombinant Human Ribonucleases P/MRP protein subunit POP1 (POP1), Truncated

ACP12524

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12524 Target NamePOP1
Target Synonyms4932434G09Rik; hPOP1; KIAA0061; MGC17365; MGC36536; POP1; POP1_HUMAN; Processing of precursor 1; Processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae); Processing of precursors 1; Ribonucleases P/MRP protein subunit homolog; Ribonucleases P/MRP protein subunit POP1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ99575
Background Information
  • Uniprot Id

    Q99575

  • Target Species

    Human

  • Target Name

    POP1

  • Target Full Name

    Ribonucleases P/MRP protein subunit POP1

  • Target Function

    Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.

  • Target Involvement

    Anauxetic dysplasia 2 (ANXD2)

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Synonyms

    4932434G09Rik; hPOP1; KIAA0061; MGC17365; MGC36536; POP1; POP1_HUMAN; Processing of precursor 1; Processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae); Processing of precursors 1; Ribonucleases P/MRP protein subunit homolog; Ribonucleases P/MRP protein subunit POP1

  • Target Background

    This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.

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