Recombinant Human RNA-binding motif protein, Y chromosome, family 1 member F/J (RBMY1F)

Uniprot Id

Q15415

Target Species

Human

Target Name

RBMY1F

Target Full Name

RNA-binding motif protein, Y chromosome, family 1 member F/J

Target Function

RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA splicing in the testis.

Target Subcellular Location

Nucleus.

Target Tissue Specificity

Testis-specific.

Target Research Area

Developmental Biology

Target Synonyms

RBMY1F; YRRM2;; RBMY1J; RNA-binding motif protein; Y chromosome; family 1 member F/J; Y chromosome RNA recognition motif 2

Target Background

This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked.