-
Chinese (Simplified)
-
English
-
German
-
Korean
-
Spanish
Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP13567 | Target Name | ROBO4 |
|---|---|---|---|
| Target Synonyms | axon guidance receptor, ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; Robo 4; ROBO4; ROBO4_HUMAN; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; Roundabout, homolog 4 (Drosophila) | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WZ75 |
|---|
Uniprot Id
Q8WZ75
Target Species
Human
Target Name
ROBO4
Target Full Name
Roundabout homolog 4
Target Function
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function.
Target Protein Families
Immunoglobulin superfamily, ROBO family
Target Tissue Specificity
Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta.
Target Synonyms
ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; Robo 4; ROBO4; ROBO4_HUMAN; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; Roundabout, axon guidance receptor, homolog 4 (Drosophila)
Target Background
Predicted to enable cell-cell adhesion mediator activity. Involved in angiogenesis and establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3.
Notification