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Recombinant Human RUN and SH3 domain-containing protein 1 (RUSC1), Truncated

ACP11617

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Specifications

Cat.No	ACP11617	Target Name	RUSC1
Target Synonyms	RUSC1; NESCARUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BVN2

Background Information

Uniprot Id

Q9BVN2
Target Species

Human
Target Name

RUSC1
Target Full Name

AP-4 complex accessory subunit RUSC1
Target Function

Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. Signaling adapter which plays a role in neuronal differentiation. Involved in regulation of NGF-dependent neurite outgrowth. May play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.
Target Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Early endosome. Cell junction, synapse, postsynaptic density. Golgi apparatus.
Target Tissue Specificity

Predominantly expressed in brain.
Target Synonyms

RUSC1; NESCARUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca
Target Background

Predicted to enable actin binding activity. Involved in protein polyubiquitination. Located in cytosol.

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Recombinant Human RUN and SH3 domain-containing protein 1 (RUSC1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human RUN and SH3 domain-containing protein 1 (RUSC1), Truncated Now

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