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| Cat.No | ACP10572 | Target Name | SAMSN1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-373 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NSI8 |
|---|
Uniprot Id
Q9NSI8
Target Species
Human
Target Name
SAMSN1
Target Full Name
SAM domain-containing protein SAMSN-1
Target Function
Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
Target Subcellular Location
Nucleus. Cytoplasm. Cell projection, ruffle.
Target Tissue Specificity
Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
Target Synonyms
HACS1; Hematopoietic adapter containing SH3 and sterile α, motif (SAM) domains 1; Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1; Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; Nuclear localization signals SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain; SAM domain containing protein SAMSN 1; SAM domain SH3 domain and nuclear localisation signals 1; SAM domain SH3 domain and nuclear localization signals 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SAMN1_HUMAN; SAMSN 1; Samsn1; SASH2; SH3 domain and nuclear localisation signals 1; SH3 domain and nuclear localization signals protein 1; SH3 SAM adaptor protein; SH3-SAM adaptor protein; SH3D6B; SLy2; Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2
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