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| Cat.No | ACP11188 | Target Name | SEMA4G |
|---|---|---|---|
| Target Synonyms | SEMA4G; KIAA1619; Semaphorin-4G | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NTN9 |
|---|
Uniprot Id
Q9NTN9
Target Species
Human
Target Name
SEMA4G
Target Full Name
Semaphorin-4G
Target Function
Cell surface receptor for PLXNB2. May play a role in axon guidance.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Semaphorin family
Target Synonyms
SEMA4G; KIAA1619; Semaphorin-4G
Target Background
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
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