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Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D)

ACP18357

Number
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Specifications


Cat.No ACP18357 Target NamePPP2R5D
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-602Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ14738
Background Information
  • Uniprot Id

    Q14738

  • Target Species

    Human

  • Target Name

    PPP2R5D

  • Target Full Name

    Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

  • Target Function

    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

  • Target Involvement

    Mental retardation, autosomal dominant 35 (MRD35)

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis.

  • Target Protein Families

    Phosphatase 2A regulatory subunit B56 family

  • Target Tissue Specificity

    Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.

  • Target Synonyms

    2A5D_HUMAN; B'delta; B56D; Delta isoform of regulatory subunit B56; protein phosphatase 2A; MGC2134; MGC8949; OTTHUMP00000039821; PP2A B subunit B' delta isoform; PP2A B subunit B56 delta isoform; PP2A B subunit isoform B''-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta; PP2A B subunit PR61 delta isoform; PP2A B subunit R5 delta isoform; PPP2R5D; Protein phosphatase 2 regulatory subunit B (B56) delta isoform; Protein phosphatase 2 regulatory subunit B delta isoform; Protein phosphatase 2 regulatory subunit B' delta; Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; TEG-271; Tex271

  • Target Background

    The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

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