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Recombinant Human Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK1), Truncated

ACP16027

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16027 Target NamePPP4R3A
Target SynonymsALPHA; Serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, FLFL1; KIAA2010; MEK1 SUPPRESSOR 1; MSTP033; P4R3A_HUMAN; PP4R3 ALPHA; PP4R3; PP4R3A; PPP4R3A; Protein phosphatase 4 regulatory subunit 3A; PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, suppressor of mek1 (Dictyostelium); smek1; Smk 1; SMK1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6IN85
Background Information
  • Uniprot Id

    Q6IN85

  • Target Species

    Human

  • Target Name

    PPP4R3A

  • Target Full Name

    Serine/threonine-protein phosphatase 4 regulatory subunit 3A

  • Target Function

    Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.

  • Target Protein Families

    SMEK family

  • Target Synonyms

    FLFL1; KIAA2010; MEK1 SUPPRESSOR 1; MSTP033; P4R3A_HUMAN; PP4R3 ALPHA; PP4R3; PP4R3A; PPP4R3A; Protein phosphatase 4 regulatory subunit 3A; PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, ALPHA; Serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); smek1; Smk 1; SMK1

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