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| Cat.No | ACP19321 | Target Name | SDCCAG3 |
|---|---|---|---|
| Target Synonyms | ENTR1; SDCCAG3; Endosome-associated-trafficking regulator 1; Antigen NY-CO-3; Serologically defined colon cancer antigen 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-435 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96C92 |
|---|
Uniprot Id
Q96C92
Target Species
Human
Target Name
ENTR1
Target Full Name
Endosome-associated-trafficking regulator 1
Target Function
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis.
Target Subcellular Location
Cytoplasm. Early endosome. Endosome. Recycling endosome. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
SDCCAG3 family
Target Tissue Specificity
Expressed in the colon (at protein level).
Target Synonyms
ENTR1; SDCCAG3; Endosome-associated-trafficking regulator 1; Antigen NY-CO-3; Serologically defined colon cancer antigen 3
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