Home Products Uncategorized Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), Truncated

Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), Truncated

ACP09444

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Specifications

Cat.No	ACP09444	Target Name	SHANK1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9Y566

Background Information

Uniprot Id

Q9Y566
Target Species

Human
Target Name

SHANK1
Target Full Name

SH3 and multiple ankyrin repeat domains protein 1
Target Function

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
Target Subcellular Location

Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
Target Protein Families

SHANK family
Target Tissue Specificity

Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously.
Target Synonyms

GKAP/SAPAP interacting protein; OTTHUMP00000174437; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHAN1_HUMAN; SHANK 1; Shank1; Shank1a; Somatostatin receptor interacting protein; Somatostatin receptor-interacting protein; SPANK 1; SPANK1; SSTR interacting protein; SSTR-interacting protein; SSTRIP; Synamon

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Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), Truncated Now

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