Home Products Recombinant Human SH3 domain-binding protein 5 (SH3BP5)

Recombinant Human SH3 domain-binding protein 5 (SH3BP5)

ACP20607

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Specifications

Cat.No	ACP20607	Target Name	SH3BP5
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-455	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60239

Background Information

Uniprot Id

O60239
Target Species

Human
Target Name

SH3BP5
Target Full Name

SH3 domain-binding protein 5
Target Function

Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Target Subcellular Location

Cytoplasmic vesicle membrane; Peripheral membrane protein. Mitochondrion.
Target Protein Families

SH3BP5 family
Target Tissue Specificity

Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate.
Target Synonyms

3BP5_HUMAN; OTTHUMP00000208289; OTTHUMP00000208291; OTTHUMP00000208294; SAB; SH3 binding protein; SH3 domain binding protein 5 (BTK associated); SH3 domain binding protein 5; SH3 domain binding protein that preferentially associates with BTK; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3 domainbinding protein 5; SH3BP 5; SH3BP-5; Sh3bp5

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Recombinant Human SH3 domain-binding protein 5 (SH3BP5)

Specifications

Immunogen Information

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