Recombinant Human SH3KBP1-binding protein 1 (SHKBP1)

ACP12748

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Specifications

Cat.No	ACP12748	Target Name	SHKBP1
Target Synonyms	PP203; Sb1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1; SHKB1_HUMAN; SHKBP1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-707
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8TBC3

Background Information

Uniprot Id

Q8TBC3
Target Species

Human
Target Name

SHKBP1
Target Full Name

SH3KBP1-binding protein 1
Target Function

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
Target Subcellular Location

Lysosome.
Target Protein Families

KCTD3 family
Target Tissue Specificity

Widely expressed.
Target Synonyms

PP203; Sb1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1; SHKB1_HUMAN; SHKBP1

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Recombinant Human SH3KBP1-binding protein 1 (SHKBP1)

Specifications

Immunogen Information

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