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| Cat.No | ACP05769 | Target Name | SLC6A20 |
|---|---|---|---|
| Target Synonyms | SLC6A20; SIT1; XT3; XTRP3; Sodium- and chloride-dependent transporter XTRP3; Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NP91 |
|---|
Uniprot Id
Q9NP91
Target Species
Human
Target Name
SLC6A20
Target Full Name
Sodium- and chloride-dependent transporter XTRP3
Target Function
Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Involved in the transport of glycine.
Target Involvement
Hyperglycinuria (HG); Iminoglycinuria (IG)
Target Subcellular Location
Apical cell membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A20 subfamily
Target Tissue Specificity
Kidney and small intestine. Expressed in the S3 segment of the proximal tubule.
Target Synonyms
SLC6A20; SIT1; XT3; XTRP3; Sodium- and chloride-dependent transporter XTRP3; Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homolog
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