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| Cat.No | ACP11902 | Target Name | SF3B5 |
|---|---|---|---|
| Target Synonyms | SF3B5; SF3B10; Splicing factor 3B subunit 5; SF3b5; Pre-mRNA-splicing factor SF3b 10 kDa subunit | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-86 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BWJ5 |
|---|
Uniprot Id
Q9BWJ5
Target Species
Human
Target Name
SF3B5
Target Full Name
Splicing factor 3B subunit 5
Target Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.
Target Subcellular Location
Nucleus.
Target Protein Families
SF3B5 family
Target Synonyms
SF3B5; SF3B10; Splicing factor 3B subunit 5; SF3b5; Pre-mRNA-splicing factor SF3b 10 kDa subunit
Target Background
Enables RNA binding activity and splicing factor binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U12-type spliceosomal complex and U2-type precatalytic spliceosome.
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