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| Cat.No | ACP15372 | Target Name | SPRED2 |
|---|---|---|---|
| Target Synonyms | SPRED2; Sprouty-related; EVH1 domain-containing protein 2; Spred-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-418 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z698 |
|---|
Uniprot Id
Q7Z698
Target Species
Human
Target Name
SPRED2
Target Full Name
Sprouty-related, EVH1 domain-containing protein 2
Target Function
Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Target Tissue Specificity
Expressed in liver, skin, small intestine, salivary gland and prostate.
Target Synonyms
SPRED2; Sprouty-related; EVH1 domain-containing protein 2; Spred-2
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