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| Cat.No | ACP08432 | Target Name | SQLE |
|---|---|---|---|
| Target Synonyms | SQLE; ERG1; Squalene monooxygenase; Squalene epoxidase; SE | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14534 |
|---|
Uniprot Id
Q14534
Target Species
Human
Target Name
SQLE
Target Full Name
Squalene monooxygenase
Target Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Target Subcellular Location
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Protein Families
Squalene monooxygenase family
Target Tissue Specificity
Detected in liver (at protein level).
Target Research Area
Cancer
Target Synonyms
SQLE; ERG1; Squalene monooxygenase; Squalene epoxidase; SE
Target Background
Enables FAD binding activity and squalene monooxygenase activity. Involved in lipid droplet formation; regulation of cell population proliferation; and sterol biosynthetic process. Located in intracellular membrane-bounded organelle. Is integral component of membrane.
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