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Recombinant Human Stromelysin-2 (MMP10)

ACP08952

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP08952 Target NameMMP10
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range99-476aaMol Weight45kD
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP09238
Background Information
  • Uniprot Id

    P09238

  • Target Species

    Human

  • Target Name

    MMP10

  • Target Full Name

    Stromelysin-2

  • Target Function

    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Peptidase M10A family

  • Target Research Area

    Developmental Biology

  • Target Synonyms

    Matrix metallopeptidase 10 (stromelysin 2); Matrix metalloprotease 10; Matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase 10; Matrix metalloproteinase-10; MMP 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL-2; SL2; STMY 2; STMY2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; StromelysinII; Transin 2; Transin-2; Transin2

  • Target Background

    This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.

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