Home Products Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), Truncated

Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), Truncated

ACP06232

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Specifications

Cat.No	ACP06232	Target Name	SV2C
Target Synonyms	SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q496J9

Background Information

Uniprot Id

Q496J9
Target Species

Human
Target Name

SV2C
Target Full Name

Synaptic vesicle glycoprotein 2C
Target Function

Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
Target Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Target Protein Families

Major facilitator superfamily
Target Synonyms

SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C

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Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), Truncated

Specifications

Immunogen Information

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