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Recombinant Human Synaptonemal complex protein SC65 (LEPREL4)

ACP13850

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13850 Target NameP3H4
Target SynonymsP3H4; LEPREL4; NOL55; SC65; Endoplasmic reticulum protein SC65; Leprecan-like protein 4; Nucleolar autoantigen No55; Prolyl 3-hydroxylase family member 4; Synaptonemal complex protein SC65FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-437
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ92791
Background Information
  • Uniprot Id

    Q92791

  • Target Species

    Human

  • Target Name

    P3H4

  • Target Full Name

    Endoplasmic reticulum protein SC65

  • Target Function

    Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.

  • Target Subcellular Location

    Endoplasmic reticulum.

  • Target Protein Families

    Leprecan family

  • Target Tissue Specificity

    Detected in fibroblasts (at protein level). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart.

  • Target Synonyms

    P3H4; LEPREL4; NOL55; SC65; Endoplasmic reticulum protein SC65; Leprecan-like protein 4; Nucleolar autoantigen No55; Prolyl 3-hydroxylase family member 4; Synaptonemal complex protein SC65

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