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| Cat.No | ACP16087 | Target Name | SYT10 |
|---|---|---|---|
| Target Synonyms | Synaptotagmin X; Synaptotagmin-10; SYT10; SYT10_HUMAN; SytX | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6XYQ8 |
|---|
Uniprot Id
Q6XYQ8
Target Species
Human
Target Name
SYT10
Target Full Name
Synaptotagmin-10
Target Function
Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis. Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.
Target Protein Families
Synaptotagmin family
Target Tissue Specificity
Expressed only in pancreas, lung and kidney.
Target Synonyms
Synaptotagmin X; Synaptotagmin-10; SYT10; SYT10_HUMAN; SytX
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