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| Cat.No | ACP05001 | Target Name | TIMD4 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Mammalian cell |
| Expression Range | 25-314aa | Mol Weight | 60.3 |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96H15 |
|---|
Uniprot Id
Q96H15
Target Species
Human
Target Name
TIMD4
Target Full Name
T-cell immunoglobulin and mucin domain-containing protein 4
Target Function
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, TIM family
Target Research Area
Immunology
Target Synonyms
SMUCKLER; Spleen; mucin-containing; knockout of lymphotoxin protein; T cell immunoglobulin and mucin domain containing protein 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing molecule; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin and mucin domains-containing protein 4; T-cell membrane protein 4; TIM-4; Tim4; TIMD 4; TIMD-4; Timd4; TIMD4_HUMAN
Target Background
Predicted to enable phosphatidylserine binding activity. Predicted to act upstream of or within apoptotic cell clearance. Predicted to be integral component of membrane.
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