Home Products Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2), Truncated

Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2), Truncated

ACP14956

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP14956	Target Name	TIAM2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IVF5

Background Information

Uniprot Id

Q8IVF5
Target Species

Human
Target Name

TIAM2
Target Full Name

Rho guanine nucleotide exchange factor TIAM2
Target Function

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
Target Subcellular Location

Cytoplasm. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Cell projection, neuron projection. Perikaryon.
Target Protein Families

TIAM family
Target Tissue Specificity

Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis.
Target Synonyms

FLJ41865; OTTHUMP00000017472; SIF and TIAM1 like exchange factor ; SIF and TIAM1-like exchange factor; STEF ; T cell lymphoma invasion and metastasis 2; T lymphoma invasion and metastasis inducing protein 2; T-lymphoma invasion and metastasis-inducing protein 2; TIAM 2; TIAM-2; Tiam2; TIAM2_HUMAN

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Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2), Truncated Now

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