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Recombinant Human Taste receptor type 2 member 43 (TAS2R43), Truncated

ACP06890

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06890 Target NameTAS2R43
Target SynonymsTAS2R43; Taste receptor type 2 member 43; T2R43; Taste receptor type 2 member 52; T2R52FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP59537
Background Information
  • Uniprot Id

    P59537

  • Target Species

    Human

  • Target Name

    TAS2R43

  • Target Full Name

    Taste receptor type 2 member 43

  • Target Function

    Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.

  • Target Protein Families

    G-protein coupled receptor T2R family

  • Target Tissue Specificity

    Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in airway epithelia.

  • Target Synonyms

    TAS2R43; Taste receptor type 2 member 43; T2R43; Taste receptor type 2 member 52; T2R52

Inquire Recombinant Human Taste receptor type 2 member 43 (TAS2R43), Truncated Now



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