Recombinant Human TATA-binding protein-associated factor 172 (BTAF1), Truncated

Uniprot Id

O14981

Target Species

Human

Target Name

BTAF1

Target Full Name

TATA-binding protein-associated factor 172

Target Function

Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner.

Target Subcellular Location

Nucleus.

Target Protein Families

SNF2/RAD54 helicase family

Target Synonyms

ATP dependent helicase BTAF1; ATP-dependent helicase BTAF1; B-TFIID transcription factor associated 170 kDa subunit ; B-TFIID transcription factor associated, 170kDa (Mot1 homolog, S. cerevisiae); B-TFIID transcription factor-associated 170 kDa subunit; BTAF 1 RNA polymerase II; BTAF1; BTAF1 RNA polymerase II B TFIID transcription factor associated 170kDa; BTAF1_HUMAN; MOT 1; MOT1; MOT1 Yeast homolog of; TAF 172; TAF II 170; TAF(II)170; TAF-172; TAF172; TAFII170; TATA binding protein associated factor 172; TATA-binding protein-associated factor 172; TBP associated factor 172; TBP-associated factor 172

Target Background

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters.