Recombinant Human Tenascin-X (TNXB)

Cat.No	ACP24133	Target Name	TNXB
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-673	Protein Length	full length protein of Isoform 2
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP24133

Target Name

TNXB

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-673

Protein Length

full length protein of Isoform 2

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P22105

Background Information

Uniprot Id

P22105
Target Species

Human
Target Name

TNXB
Target Full Name

Tenascin-X
Target Function

Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors.
Target Involvement

Ehlers-Danlos syndrome due to tenascin X deficiency (EDSTNXD); Vesicoureteral reflux 8 (VUR8)
Target Subcellular Location

Secreted, extracellular space, extracellular matrix.
Target Protein Families

Tenascin family
Target Tissue Specificity

Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

EDS3; Ehlers Danlos like syndrome; Growth inhibiting protein 45; Hexabrachion like protein; Hexabrachion-like protein; HXBL; NXB2; Tenascin X; Tenascin X precursor; Tenascin XB; Tenascin XB1; Tenascin XB2; Tenascin-X; TENX; TENX_HUMAN; TN X; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
Target Background

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.

Recombinant Human Tenascin-X (TNXB)

Specifications

Immunogen Information

Inquire Recombinant Human Tenascin-X (TNXB) Now

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