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Recombinant Human Threonine–tRNA ligase, mitochondrial (TARS2), Truncated

ACP02754

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Specifications

Cat.No	ACP02754	Target Name	TARS2
Target Synonyms	TARS2; TARSL1; Threonine--tRNA ligase; mitochondrial; EC 6.1.1.3; Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	369-718aa
Mol Weight	55.3kDa	Protein Length	Partial
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BW92

Background Information

Uniprot Id

Q9BW92
Target Species

Human
Target Name

TARS2
Target Full Name

Threonine--tRNA ligase, mitochondrial
Target Function

Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
Target Involvement

Combined oxidative phosphorylation deficiency 21 (COXPD21)
Target Subcellular Location

Mitochondrion matrix.
Target Protein Families

Class-II aminoacyl-tRNA synthetase family
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

TARS2; TARSL1; Threonine--tRNA ligase; mitochondrial; EC 6.1.1.3; Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1
Target Background

This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.

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Recombinant Human Threonine–tRNA ligase, mitochondrial (TARS2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Threonine–tRNA ligase, mitochondrial (TARS2), Truncated Now

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