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| Cat.No | ACP10076 | Target Name | TRAK1 |
|---|---|---|---|
| Target Synonyms | TRAK1; KIAA1042; OIP106; Trafficking kinesin-binding protein 1; 106 kDa O-GlcNAc transferase-interacting protein; Protein Milton | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UPV9 |
|---|
Uniprot Id
Q9UPV9
Target Species
Human
Target Name
TRAK1
Target Full Name
Trafficking kinesin-binding protein 1
Target Function
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.
Target Subcellular Location
Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Mitochondrion membrane. Cytoplasm, cell cortex.
Target Tissue Specificity
High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.
Target Synonyms
TRAK1; KIAA1042; OIP106; Trafficking kinesin-binding protein 1; 106 kDa O-GlcNAc transferase-interacting protein; Protein Milton
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