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| Cat.No | ACP02342 | Target Name | TCN1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 24-433aa | Mol Weight | 61.6kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20061 |
|---|
Uniprot Id
P20061
Target Species
Human
Target Name
TCN1
Target Full Name
Transcobalamin-1
Target Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Target Subcellular Location
Secreted.
Target Protein Families
Eukaryotic cobalamin transport proteins family
Target Tissue Specificity
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Target Research Area
Signal Transduction
Target Synonyms
Haptocorin; Haptocorrin; HC; OTTHUMP00000235879; TC 1; TC I; TC-1; TC1; TCI; TCN 1; TCN1; TCO1_HUMAN; Transcobalamin 1; Transcobalamin I; Transcobalamin-1; Transcobalamin1; TranscobalaminI; Vitamin B12 binding protein; Vitamin B12 binding protein R binder family
Target Background
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
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