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| Cat.No | ACP21550 | Target Name | TFEC |
|---|---|---|---|
| Target Synonyms | bHLHe34; Class E basic helix-loop-helix protein 34; hTFEC-L; TCFEC; TFE-C; Tfec; TFEC protein; TFEC_HUMAN; TFECL; Transcription factor EC; Transcription factor EC-like | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-347 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14948 |
|---|
Uniprot Id
O14948
Target Species
Human
Target Name
TFEC
Target Full Name
Transcription factor EC
Target Function
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Target Subcellular Location
Nucleus.
Target Protein Families
MiT/TFE family
Target Tissue Specificity
Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
Target Synonyms
bHLHe34; Class E basic helix-loop-helix protein 34; hTFEC-L; TCFEC; TFE-C; Tfec; TFEC protein; TFEC_HUMAN; TFECL; Transcription factor EC; Transcription factor EC-like
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