Recombinant Human Transcriptional activator Myb (MYB)

Uniprot Id

P10242

Target Species

Human

Target Name

MYB

Target Full Name

Transcriptional activator Myb

Target Function

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Target Subcellular Location

Nucleus.

Target Synonyms

C myb; c myb protein (140 AA); c-myb protein (140 AA); c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; Cmyb; efg; Myb; MYB proto-oncogene transcription factor; MYB_HUMAN; ONCOGENE AMV; Oncogene MYB; Proto oncogene c Myb; Proto-oncogene c-Myb; Transcriptional activator Myb; v myb avian myeloblastosis viral oncogene homolog; v-myb avian myeloblastosis viral oncogene homolog

Target Background

This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.